benzyl piperidin-4-ylcarbamate
4-Cbz-Aminopiperidine
CAS: 182223-54-7
Molecular Formula: C13H18N2O2
benzyl piperidin-4-ylcarbamate - Names and Identifiers
| Name | 4-Cbz-Aminopiperidine |
| Synonyms | 4-CBZ-AMINOPIPERIDINE 4-Cbz-Aminopiperidine N-CBZ-piperidin-4-aMine benzyl piperidin-4-ylcarbamate benzyl N-(piperidin-4-yl)carbaMate 4-Benzyloxycarbonylamino-piperdine 4-BENZYLOXYCARBONYLAMINO-PIPERIDINE benzyl piperidin-4-ylcarbamate hydrochloride Carbamic acid, 4-piperidinyl-, phenylmethyl ester Carbamic acid, 4-piperidinyl-, phenylmethyl ester (9CI) |
| CAS | 182223-54-7 |
| InChI | InChI=1/C13H18N2O2/c16-13(15-12-6-8-14-9-7-12)17-10-11-4-2-1-3-5-11/h1-5,12,14H,6-10H2,(H,15,16) |
benzyl piperidin-4-ylcarbamate - Physico-chemical Properties
| Molecular Formula | C13H18N2O2 |
| Molar Mass | 234.29 |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Boling Point | 396.3±41.0 °C(Predicted) |
| Flash Point | 193.5°C |
| Solubility | Dichloromethane |
| Vapor Presure | 1.73E-06mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| pKa | 12.18±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.557 |
benzyl piperidin-4-ylcarbamate - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29333990 |
benzyl piperidin-4-ylcarbamate - Introduction
4-Cbz-Aminopiperidine is an organic compound with the chemical formula C16H18N2O2 and a molecular weight of 270.33g/mol. It is a white crystalline solid, insoluble in water and soluble in organic solvents.
This compound is often used as a drug intermediate and has important application value in drug research and development. Specific uses include synthetic anticancer drugs, antiviral drugs, antibacterial drugs, etc. It can be used as an important active group to participate in drug molecules and enhance their efficacy.
There are two main methods for preparing 4-Cbz-Aminopiperidine: one is to react with benzylchloroformate by aminopiperidine to generate 4-Cbz-Aminopiperidine; The other is to react with chloroformyl chloride by aminopiperidine, aminopiperidinecarbonyl chloride is obtained, followed by reaction with benzyl alcohol to give 4-Cbz-Aminopiperidine.
During the operation, you need to pay attention to the safety of 4-Cbz-Aminopiperidine. The compound is irritating and avoids contact with skin and eyes. Appropriate protective measures, such as lab clothes, gloves and goggles, must be worn during the experiment. At the same time, for its further application in drug development, more detailed toxicological and biological evaluation is needed to ensure safety and efficacy.
This compound is often used as a drug intermediate and has important application value in drug research and development. Specific uses include synthetic anticancer drugs, antiviral drugs, antibacterial drugs, etc. It can be used as an important active group to participate in drug molecules and enhance their efficacy.
There are two main methods for preparing 4-Cbz-Aminopiperidine: one is to react with benzylchloroformate by aminopiperidine to generate 4-Cbz-Aminopiperidine; The other is to react with chloroformyl chloride by aminopiperidine, aminopiperidinecarbonyl chloride is obtained, followed by reaction with benzyl alcohol to give 4-Cbz-Aminopiperidine.
During the operation, you need to pay attention to the safety of 4-Cbz-Aminopiperidine. The compound is irritating and avoids contact with skin and eyes. Appropriate protective measures, such as lab clothes, gloves and goggles, must be worn during the experiment. At the same time, for its further application in drug development, more detailed toxicological and biological evaluation is needed to ensure safety and efficacy.
Last Update：2024-04-09 19:05:47
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CAS: 182223-54-7
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CAS: 182223-54-7
Tel: 18301782025
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Mobile: 18021002903
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